Cover Image

Primary hypoparathyroidism presenting as basal ganglia calcification secondary to extreme hypocalcemia

Edite Marques Mendes, Lúcia Meireles-Brandão, Carla Meira, Nuno Morais, Carlos Ribeiro, Diana Guerra
  • Edite Marques Mendes
    Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal | editemarquesmendes@gmail.com
  • Lúcia Meireles-Brandão
    Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal
  • Carla Meira
    Department of Medicine - Intermediate Care Unit, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal
  • Nuno Morais
    Department of Medicine - Intermediate Care Unit, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal
  • Carlos Ribeiro
    Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal
  • Diana Guerra
    Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal

Abstract

Hypoparathyroidism is a rare endocrine disorder characterized by low serum calcium and parathyroid hormone levels. The most common cause is parathyroid iatrogenic surgical removal. However, innumerous and rarer conditions can cause hypoparathyroidism. The authors describe a 27-year-old man that presented in emergency department with confusion, amnesia and decreased attention span. A cerebral computed tomography revealed bilateral extensive calcification in the basal ganglia. A complete work-up revealed low serum calcium, high serum phosphorus and low parathyroid hormone, leading to the diagnosis of idiopathic primary hypoparathyroidism. Initial intravenous therapy with calcium gluconate and calcitriol was administered, with clinical and analytical improvement. The authors describe a rare condition, with an exuberant cerebral presentation and extreme hypocalcemia, which did not directly correlate to the severity of symptoms. Not only this is a treatable disorder that may have catastrophic results if overlooked but also its symptoms may be completely reversed with prompt treatment.

Keywords

Primary hypoparathyroidism; hypocalcemia; basal ganglia calcifications.

Full Text:

PDF
HTML
Submitted: 2017-07-17 20:22:21
Published: 2018-01-08 09:26:50
Search for citations in Google Scholar
Related articles: Google Scholar
Abstract views:
211

Views:
PDF
29
HTML
4

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM


Copyright (c) 2018 Edite Marques Mendes, Lúcia Meireles-Brandão, Carla Meira, Nuno Morais, Carlos Ribeiro, Diana Guerra

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
 
© PAGEPress 2008-2018     -     PAGEPress is a registered trademark property of PAGEPress srl, Italy.     -     VAT: IT02125780185