Revisiting transthyretin related cardiac amyloidosis: Case report and review of literature

Main Article Content

Munish Sharma(1*), Eduard Koman(2), Gary S. Ledley(3), Sung-Hae Cho(4)

1 1Department of Internal Medicine, Easton Hospital, Easton, PA, United States.
2 Department of Medicine-Division of Cardiology, Drexel University College of Medicine-Hahnemann University Hospital, Philadelphia, PA, United States.
3 Department of Medicine-Division of Cardiology, Drexel University College of Medicine-Hahnemann University Hospital, Philadelphia, PA, United States.
4 Department of Medicine-Division of Cardiology, Drexel University College of Medicine-Hahnemann University Hospital, Philadelphia, PA, United States.
(*) Corresponding Author:
Munish Sharma
munishs1@hotmail.com

Abstract

Amyloidosis is a complex group of disorders that can involve many organs and cause their dysfunction. Cardiac involvement indicates worse prognosis and influences treatment strategies. Cardiac amyloidosis is an under-diagnosed entity and high index of clinical suspicion and careful interpretation of basic diagnostic tools such as electrocardiogram and echocardiography is needed for early detection. Congestive heart failure due to restrictive pattern and/or conduction system abnormality, in absence of coronary artery disease should raise suspicion. We present a case of transthyretin related cardiac amyloidosis and discuss the key clinical and diagnostic findings along with review of existing literature regarding its management and outcomes.


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How to Cite
Sharma, M., Koman, E., Ledley, G. S., & Cho, S.-H. (2018). Revisiting transthyretin related cardiac amyloidosis: Case report and review of literature. Clinics and Practice, 8(2). https://doi.org/10.4081/cp.2018.1054