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Acute promyelocytic leukemia, hypogranular variant: a rare presentation

Kafil Akhtar, Shamshad Ahmad, Rana K. Sherwani
  • Kafil Akhtar
    Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh (UP)-India, India | drkafilakhtar@gmail.com
  • Shamshad Ahmad
    Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh (UP)-India, India
  • Rana K. Sherwani
    Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh (UP)-India, India

Abstract

Early diagnosis of acute promyelocytic leukemia (APL) is essential because of its associated life threatening coagulopathy and unique response to all trans-retinoic acid (ATRA) therapy. The characteristic cell morphology supplemented by cytochemistry offers the most rapid means for diagnosis. Here we describe a rare case of acute promyelocytic leukemia-hypogranular variant that poses particular diagnostic challenge.

Keywords

acute promyelocytic leukemia, hypogranular variant, cytochemistry.

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Submitted: 2011-03-11 05:51:59
Published: 2011-04-12 15:08:51
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Copyright (c) 2011 Kafil Akhtar, Shamshad Ahmad, Rana K. Sherwani

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