Gut microbiota’s effect on mental health: The gut-brain axis

Main Article Content

Megan Clapp(1*), Nadia Aurora(2), Lindsey Herrera(3), Manisha Bhatia(4), Emily Wilen(5), Sarah Wakefield(6)

1 School of Medicine, Health Sciences Center, Texas Tech University, TX, United States.
2 School of Medicine, Health Sciences Center, Texas Tech University, TX, United States.
3 School of Medicine, Health Sciences Center, Texas Tech University, TX, United States.
4 School of Medicine, Health Sciences Center, Texas Tech University, TX, United States.
5 School of Medicine, Health Sciences Center, Texas Tech University, TX, United States.
6 Department of Psychiatry, Health Sciences Center, Texas Tech University, TX, United States.
(*) Corresponding Author:
Megan Clapp
megan.clapp@ttuhsc.edu

Abstract

The bidirectional communication between the central nervous system and gut microbiota, referred to as the gut-brain-axis, has been of significant interest in recent years. Increasing evidence has associated gut microbiota to both gastrointestinal and extragastrointestinal diseases. Dysbiosis and inflammation of the gut have been linked to causing several mental illnesses including anxiety and depression, which are prevalent in society today. Probiotics have the ability to restore normal microbial balance, and therefore have a potential role in the treatment and prevention of anxiety and depression. This review aims to discuss the development of the gut microbiota, the linkage of dysbiosis to anxiety and depression, and possible applications of probiotics to reduce symptoms.

Downloads month by month

Downloads

Download data is not yet available.

Article Details

How to Cite
Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E., & Wakefield, S. (2017). Gut microbiota’s effect on mental health: The gut-brain axis. Clinics and Practice, 7(4). https://doi.org/10.4081/cp.2017.987
Author Biography

Sarah Wakefield, Department of Psychiatry, Health Sciences Center, Texas Tech University, TX

Assistant Professor of Psychiatry