Primary hypoparathyroidism presenting as basal ganglia calcification secondary to extreme hypocalcemia

  • Edite Marques Mendes | editemarquesmendes@gmail.com Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal.
  • Lúcia Meireles-Brandão Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal.
  • Carla Meira Department of Medicine - Intermediate Care Unit, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal.
  • Nuno Morais Department of Medicine - Intermediate Care Unit, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal.
  • Carlos Ribeiro Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal.
  • Diana Guerra Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal.

Abstract

Hypoparathyroidism is a rare endocrine disorder characterized by low serum calcium and parathyroid hormone levels. The most common cause is parathyroid iatrogenic surgical removal. However, innumerous and rarer conditions can cause hypoparathyroidism. The authors describe a 27-year-old man that presented in emergency department with confusion, amnesia and decreased attention span. A cerebral computed tomography revealed bilateral extensive calcification in the basal ganglia. A complete work-up revealed low serum calcium, high serum phosphorus and low parathyroid hormone, leading to the diagnosis of idiopathic primary hypoparathyroidism. Initial intravenous therapy with calcium gluconate and calcitriol was administered, with clinical and analytical improvement. The authors describe a rare condition, with an exuberant cerebral presentation and extreme hypocalcemia, which did not directly correlate to the severity of symptoms. Not only this is a treatable disorder that may have catastrophic results if overlooked but also its symptoms may be completely reversed with prompt treatment.

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Author Biography

Edite Marques Mendes, Department of Medicine - Medicine 1, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo
Departamento de Medicina 1.
Published
2018-01-08
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Section
Case Reports
Keywords:
Primary hypoparathyroidism, hypocalcemia, basal ganglia calcifications.
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How to Cite
Marques Mendes, E., Meireles-Brandão, L., Meira, C., Morais, N., Ribeiro, C., & Guerra, D. (2018). Primary hypoparathyroidism presenting as basal ganglia calcification secondary to extreme hypocalcemia. Clinics and Practice, 8(1). https://doi.org/10.4081/cp.2018.1007