Revisiting transthyretin related cardiac amyloidosis: Case report and review of literature

  • Munish Sharma | munishs1@hotmail.com Department of Internal Medicine, Easton Hospital, Easton, PA, United States.
  • Eduard Koman Department of Medicine-Division of Cardiology, Drexel University College of Medicine-Hahnemann University Hospital, Philadelphia, PA, United States.
  • Gary S. Ledley Department of Medicine-Division of Cardiology, Drexel University College of Medicine-Hahnemann University Hospital, Philadelphia, PA, United States.
  • Sung-Hae Cho Department of Medicine-Division of Cardiology, Drexel University College of Medicine-Hahnemann University Hospital, Philadelphia, PA, United States.

Abstract

Amyloidosis is a complex group of disorders that can involve many organs and cause their dysfunction. Cardiac involvement indicates worse prognosis and influences treatment strategies. Cardiac amyloidosis is an under-diagnosed entity and high index of clinical suspicion and careful interpretation of basic diagnostic tools such as electrocardiogram and echocardiography is needed for early detection. Congestive heart failure due to restrictive pattern and/or conduction system abnormality, in absence of coronary artery disease should raise suspicion. We present a case of transthyretin related cardiac amyloidosis and discuss the key clinical and diagnostic findings along with review of existing literature regarding its management and outcomes.

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Published
2018-05-16
Section
Case Reports
Keywords:
Cardiac amyloidosis, endomyocardial biopsy, cardiac magnetic resonance imaging, ECG findings in cardiac amyloidosis.
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How to Cite
Sharma, M., Koman, E., Ledley, G. S., & Cho, S.-H. (2018). Revisiting transthyretin related cardiac amyloidosis: Case report and review of literature. Clinics and Practice, 8(2). https://doi.org/10.4081/cp.2018.1054

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