Acute eosinophilic appendicitis after generalized skin reaction due to unknown cause in a child: Case report and literature review

  • Maria Aggelidou | marartem@yahoo.gr Department of Pediatric Surgery, Democritus University of Thrace, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.
  • Katerina Kambouri Department of Pediatric Surgery, Democritus University of Thrace, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.
  • Maria Kouroupi Department of Pathology, Democritus University of Thrace, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.
  • Dimitrios Cassimos Department of Pediatrics, Democritus University of Thrace, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.
  • Soultana Foutzitzi Department of Radiology, Democritus University of Thrace, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.
  • Savas Deftereos Department of Radiology, Democritus University of Thrace, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.

Abstract

Acute eosinophilic appendicitis (AEA) is a rare variant of appendix inflammation possibly linked to allergy. Histopathological evidence of eosinophilic infiltration of the muscularis propria and edema separating the muscle fibers is the gold standard for the diagnosis. Here, we report a case of a young boy with AEA following a skin reaction of possible allergic origin. A 6-year-old male was presented to the emergency department with a two-day diffuse abdominal pain and tenderness in the right lower quadrant. A possible allergic reaction had occurred five days before as a pruritic rash. There was no history of allergy and the stool examination was negative for parasites. The initial diagnosis was acute appendicitis, and appendectomy was performed. The histopathological diagnosis was AEA. Further studies on the proper diagnostic and treatment approach of AEA before surgery are required.

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Published
2019-09-16
Section
Case Reports
Keywords:
Acute eosinophilic appendicitis, Allergy, Children
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How to Cite
Aggelidou, M., Kambouri, K., Kouroupi, M., Cassimos, D., Foutzitzi, S., & Deftereos, S. (2019). Acute eosinophilic appendicitis after generalized skin reaction due to unknown cause in a child: Case report and literature review. Clinics and Practice, 9(3). https://doi.org/10.4081/cp.2019.1177