Multiple extra-splanchnic venous thromboses - an unusual vascular complication of acute pancreatitis

  • Junare Parmeshwar Ramesh | parmeshwarjunare.717@gmail.com Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India. https://orcid.org/0000-0001-6393-2399
  • Chandnani Sanjay Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India.
  • Suhas Udgirkar Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India.
  • Nair Sujit Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India. https://orcid.org/0000-0002-2993-7353
  • Debnath Prasanta Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India. https://orcid.org/0000-0001-8294-2031
  • Modi Ammar Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India.
  • Debnath Partha Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India. https://orcid.org/0000-0001-6367-545X
  • Jain Shubham Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India. https://orcid.org/0000-0001-9484-7568
  • Ravi Thanage Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India. https://orcid.org/0000-0003-0669-2063
  • Rathi Pravin Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India.
  • Contractor Qais Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, India.

Abstract

Acute pancreatitis (AP) is an acute inflammatory process of the pancreas with variable clinical presentations. Splanchnic venous thrombosis is a well-known vascular complication of AP and commonly present as thrombosis of the splanchnic venous system: splenic vein (SplV), portal vein (PV) and superior mesenteric vein (SMV), either separately or in combinations. Involvement of extra-splanchnic vessels is rare and associated with morbidity and mortality. Vascular complications are late phenomena and usually associated with local complications of AP, namely acute fluid collections, necrotizing pancreatitis and walled-off pancreatic necrosis. Pathogenesis of venous thrombosis is multifactorial in which pancreatic inflammation and systemic inflammatory response play a key role. At present, there are no consensus guidelines on treatment and use of anticoagulation for venous thrombosis in the setting of AP. Limited literature suggests the use of anticoagulation in presence of PV with or without SMV thrombosis and extrasplanchnic vessel involvement. Literature on extra-splanchnic vessels involvement in acute pancreatitis is sparse. Here we present two cases with multiple extra-splanchnic vessels involvement and their management.

Google Scholar

Google Scholar

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2020-09-28
Info
Issue
Section
Case Reports
Keywords:
Acute pancreatitis, extra-splanchnic venous thrombosis, splanchnic venous thrombosis.
Statistics
  • Abstract views: 85

  • PDF: 48
  • HTML: 0
How to Cite
Parmeshwar Ramesh, J., Sanjay, C., Udgirkar, S., Sujit, N., Prasanta, D., Ammar, M., Partha, D., Shubham, J., Thanage, R., Pravin, R., & Qais, C. (2020). Multiple extra-splanchnic venous thromboses - an unusual vascular complication of acute pancreatitis. Clinics and Practice, 10(3). https://doi.org/10.4081/cp.2020.1226