Use of therapeutic surfactant lavage in a preterm infant with massive pulmonary hemorrhage

  • Ino Kanavaki | ino.kanavaki@hcuge.ch Pediatric and Neonatal Intensive Care Unit, Department of Pediatrics, University Hospital of Geneva, Switzerland.
  • Laszlo Vutskits Department of Anaesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Switzerland.
  • Peter C. Rimensberger Pediatric and Neonatal Intensive Care Unit, Department of Pediatrics, University Hospital of Geneva, Switzerland.

Abstract

We report a case of a premature infant presenting with recurrent pulmonary hemorrhage in which we performed a therapeutic lavage with diluted surfactant after an acute episode of bleeding with severe intractable hypoxemia. Repeated small aliquots of diluted surfactant (10x2 mL) allowed rapid improvement in oxygenation and reduction of required mean airway pressures during high frequency oscillatory ventilation. This observation may suggest that surfactant lavage could be beneficial in massive pulmonary hemorrhage in infants. A randomized controlled trial might be needed to clarify the potential benefit of this therapeutic intervention on outcome of infants suffering from this life-threatening complication.

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Published
2012-08-06
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Section
Case Reports
Keywords:
pulmonary hemorrhage, surfactant lavage, prematurity.
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How to Cite
Kanavaki, I., Vutskits, L., & Rimensberger, P. C. (2012). Use of therapeutic surfactant lavage in a preterm infant with massive pulmonary hemorrhage. Clinics and Practice, 2(3), e74. https://doi.org/10.4081/cp.2012.e74