Invasive pneumococcal infection despite 7-valent conjugated vaccine

  • Sebastien Joye Department of Pediatrics, University Hospital of Lausanne (CHUV), Switzerland.
  • Anja Gao Department of Pediatrics, University Hospital of Lausanne (CHUV), Switzerland.
  • Simon Kayemba-Kay's Department of Pediatrics, University Hospital of Lausanne (CHUV), Switzerland.
  • Jacques Cotting Pediatric Intensive Care Unit, University Hospital of Lausanne (CHUV), Switzerland.
  • Marie-Hélène Perez | marie-helene.perez@chuv.ch Pediatric Intensive Care Unit, University Hospital of Lausanne (CHUV), Switzerland.

Abstract

Despite good cover with 7-valent vaccination, invasive pneumococcal infections may still be misdiagnosed and may lead to lifethreatening situations or death in young children. New serotypes are emerging and, therefore, clinicians must keep a high level of suspicion in young children regardless of their vaccination status. We report three cases of invasive pneumococcal infection due to new serotypes not covered by the 7-valent conjugated vaccine, two of which led children to death.

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Author Biographies

Sebastien Joye, Department of Pediatrics, University Hospital of Lausanne (CHUV)
Physician
Anja Gao, Department of Pediatrics, University Hospital of Lausanne (CHUV)
Physician
Simon Kayemba-Kay's, Department of Pediatrics, University Hospital of Lausanne (CHUV)

Head Physician of Pediatrics and Neonatology
Head physician of Pediatric Endocrinology

Jacques Cotting, Pediatric Intensive Care Unit, University Hospital of Lausanne (CHUV)
Head staff of Pediatric Intensive Care Unit
Marie-Hélène Perez, Pediatric Intensive Care Unit, University Hospital of Lausanne (CHUV)

Staff of the Pediatric Intensive Care Unit

Published
2013-03-25
Section
Case Reports
Keywords:
Streptococcus Pneumoniae, 7-valent conjugated vaccine, sepsis, meningitis.
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How to Cite
Joye, S., Gao, A., Kayemba-Kay’s, S., Cotting, J., & Perez, M.-H. (2013). Invasive pneumococcal infection despite 7-valent conjugated vaccine. Clinics and Practice, 3(1), e11. https://doi.org/10.4081/cp.2013.e11