Computed tomography-guided cryoablation of local recurrence after primary resection of pancreatic adenocarcinoma

  • Claudio Pusceddu Division of Interventional Radiology, Department of Oncological Radiology, Oncological Hospital A. Businco, Cagliari, Italy.
  • Luca Melis Division of Interventional Radiology, Department of Oncological Radiology, Oncological Hospital A. Businco, Cagliari, Italy.
  • Barbara Sotgia Division of Interventional Radiology, Department of Oncological Radiology, Oncological Hospital A. Businco, Cagliari, Italy.
  • Alessandro Fancellu | afancel@uniss.it Unit of General Surgery 2, Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.
  • Giovanni Battista Meloni Institute of Radiological Sciences, University of Sassari, Sassari, Italy.

Abstract

The optimal management of local recurrences after primary resection of pancreatic cancer still remains to be clarified. A 58-yearold woman developed an isolated recurrence of pancreatic cancer six year after distal pancreatectomy. Re-resection was attempted but the lesion was deemed unresectable at surgery. Then chemotherapy was administrated without obtaining a reduction of the tumor size nor an improvement of the patient’s symptoms. Thus the patient underwent percutaneous cryoablation under computed tomography (CT)-guidance obtaining tumor necrosis and a significant improvement in the quality of life. A CT scan one month later showed a stable lesion with no contrast enhancement. While the use of percutaneous cryoblation has widened its applications in patients with unresectable pancreatic cancer, it has never been described for the treatment of local pancreatic cancer recurrence after primary resection. Percutaneous cryoablation deserves further studies in the multimodality treatment of local recurrence after primary pancreatic surgery.

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Published
2015-06-23
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Section
Case Reports
Keywords:
Pancreatic cancer, recurrence, percutaneous cryoablation, computed tomography scan.
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How to Cite
Pusceddu, C., Melis, L., Sotgia, B., Fancellu, A., & Meloni, G. B. (2015). Computed tomography-guided cryoablation of local recurrence after primary resection of pancreatic adenocarcinoma. Clinics and Practice, 5(2). https://doi.org/10.4081/cp.2015.741