Enlarging pancreatic schwannoma: a case report and review of the literature

  • Narjust Duma | narjustperezmd@gmail.com Rutgers-New Jersey Medical School, Newark, NJ, United States.
  • Daniel C. Ramirez Rutgers-New Jersey Medical School, Newark, NJ, United States.
  • Gloria Young Hackensack University Medical Center, Hackensack, NJ, United States.
  • George Nikias Hackensack University Medical Center, Hackensack, NJ, United States.
  • Martin Karpeh Hackensack University Medical Center, Hackensack, NJ, United States.
  • Zubin M. Bamboat Hackensack University Medical Center, Hackensack, NJ, United States.

Abstract

A 72-year-old female presented with dyspepsia for 2 years and an incidental mass in the head of the pancreas on abdominal computed tomography (CT) scan. Patient had multiple negative endoscopic ultrasound guided biopsies. She was followed up for 3 years with serial imaging until an abdominal CT scan showed an increase in size of the pancreatic mass. Physical examination was unremarkable. Laboratory tests including tumor markers were normal. Given the enlarging size of the mass and its impingement on the portal vein, the consensus was to proceed with surgery. Histology revealed a 3.5 cm mass showing a spindle cell neoplasm with mild atypia. The lesion was well defined and nerve tissue was noted at the periphery. On immuno-stains, the spindle cells were positive for S-100 protein and negative for pan-cytokeratin, CD-34, CD- 117, smooth muscle actin and Melan A, consistent with the diagnosis of a pancreatic schwannoma.

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Published
2015-12-28
Section
Case Reports
Keywords:
Pancreatic schwannoma, nerve tissue tumors, pancreatic mass, neurilemmomas.
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How to Cite
Duma, N., Ramirez, D., Young, G., Nikias, G., Karpeh, M., & Bamboat, Z. (2015). Enlarging pancreatic schwannoma: a case report and review of the literature. Clinics and Practice, 5(4). https://doi.org/10.4081/cp.2015.793