Oncocytic pleomorphic adenoma of palatal salivary gland with macrophages and giant cells associated with cholesterol crystals

  • Gargi S. Sarode Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Maharashtra, India.
  • Sachin C. Sarode | drsachinsarode@gmail.com Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Maharashtra, India. http://orcid.org/0000-0003-1856-0957
  • Shankargouda Patil Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Saudi Arabia.
  • Sukumaran Anil Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University, Saudi Arabia.

Abstract

Pleomorphic adenoma (PA) is the most common salivary gland tumor characterized by histo-morphological diversity in the form of myxoid, hyalinized, chondroid, osseous, and squamous areas. In this paper, we report a rare case of predominantly oncocytic variant of PA in a 45-year-old male patient on the posterior palatal region. Microscopic examination showed homogenous eosinophilic cellular mass composed of epithelial components arranged in the form of tubular and solid patterns. The polygonal and oval cells showed abundant dark eosinophilic granular cytoplasm. The cell borders were distinct with a central nucleus showing prominent nucleoli. Interestingly at few places, cholesterol clefts were seen surrounded by macrophages and giant cells. The tumor was surgically excised with no evidence of recurrence after 2 years.

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Author Biographies

Gargi S. Sarode, Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Maharashtra

Associate Professor

Department of Oral Pathology and Microbiology

Sachin C. Sarode, Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Maharashtra

Professor

Department of Oral Pathology and Microbiolgy

Published
2016-10-24
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Section
Case Reports
Keywords:
Salivary gland tumor, pleomorphic adenoma, oncocytes, cholesterol crystals.
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How to Cite
Sarode, G. S., Sarode, S. C., Patil, S., & Anil, S. (2016). Oncocytic pleomorphic adenoma of palatal salivary gland with macrophages and giant cells associated with cholesterol crystals. Clinics and Practice, 6(4). https://doi.org/10.4081/cp.2016.884

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