A moderate response to plasmapheresis in nephrogenic systemic fibrosis

  • Pelin Ustuner | pelindogaustuner@gmail.com Department of Dermatology, Faculty of Medicine, Baskent University, Ankara, Turkey.
  • Ozlem Karadag Kose Department of Dermatology, Faculty of Medicine, Baskent University, Ankara, Turkey.
  • A. Tulin Gulec Department of Dermatology, Faculty of Medicine, Baskent University, Ankara, Turkey.
  • Ozlem Ozen Department of Pathology, Faculty of Medicine, Baskent University, Ankara, Turkey.

Abstract

Nephrogenic systemic fibrosis (NSF) is a recently identified idiopathic cutaneous fibrosing disorder that occurs in the setting of renal failure. The disease initially called nephrogenic fibrosing dermopathy is closely linked to exposure to gadolinium-based contrast media used during magnetic resonance imaging in patients with renal insufficiency. Although little is known about the pathogenesis of this disease, the increased expression of transforming growth factor-beta has been demonstrated recently. Herein, we present a case of NSF was partially treated due to a moderate and temporary response to plasmapheresis with no recurrence for 6 months, but returned at the end of 6th month.

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Published
2011-11-29
Section
Case Reports
Keywords:
nephrogenic fibrosing dermopathy, plasmapheresis, transforming growth factors.
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How to Cite
Ustuner, P., Kose, O., Gulec, A. T., & Ozen, O. (2011). A moderate response to plasmapheresis in nephrogenic systemic fibrosis. Clinics and Practice, 1(4), e124. https://doi.org/10.4081/cp.2011.e124