Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease

  • Sarwan Kumar | skumar2@med.wayne.edu Department of Internal Medicine, Wayne State University/Detroit Medical Center, .
  • Deepak Gupta Department of Anesthesiology, Wayne State University/Detroit Medical Center, United States.
  • Shiva S. Rau Department of Internal Medicine, Wayne State University/Detroit Medical Center, .

Abstract

This case highlights the fact that Supratherapeutic INRs direct the attention of the treating physicians’ team to the underlying severely debilitating gastrointestinal diseases. Prolonged fasting or starvation reduces vitamin K levels. Such patients are more sensitive to treatment with Vitamin K antagonist-based anticoagulants. Hence, the Supratherapeutic INR can be an objective indicator of chronic loss of appetite with poor nutritional status of the patient and therefore acts as a warning sign for diagnosis of severe debilitating primary gastrointestinal disease.

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Published
2011-04-19
Section
Case Reports
Keywords:
Supratherapeutic INRs
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How to Cite
Kumar, S., Gupta, D., & Rau, S. (2011). Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease. Clinics and Practice, 1(2), e21. https://doi.org/10.4081/cp.2011.e21