Primary pineal malignant melanoma

  • Oderay Mabel Cedeño Díaz | omcedeno@fjd.es Surgical Pathology, Gregorio Marañon General Hospital, Madrid, Spain.
  • Roberto Garcia Leal Neurosurgery, Gregorio Marañon General Hospital, Madrid, Spain.
  • Cesar La Cruz Pelea Surgical Pathology, Gregorio Marañon General Hospital, Madrid, Spain.

Abstract

Primary pineal malignant melanoma is a rare entity, with only thirteen cases reported in the world literature to date. We report a case of a 70-year-old man, who consulted with gait disturbance of six months duration, associated in the last month with dizziness, visual abnormalities and diplopia. No other additional melanocytic lesions were found elsewhere. The magnetic resonance showed a 25 mm expansive mass in the pineal gland that was associated with hydrocephaly, ventricular and transependimary oedema. The lesion was partially excised by a supracerebellar infratentorial approach. The histological examination revealed a melanoma. The patient received radiation therapy, but died of disease 16 weeks later. We herein review the literature on this rare tumour and comment on its clinical, radiological and histopathological features and differential diagnosis.

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Author Biographies

Oderay Mabel Cedeño Díaz, Surgical Pathology, Gregorio Marañon General Hospital, Madrid

Department of Surgical Pathology. Pathologist.

Roberto Garcia Leal, Neurosurgery, Gregorio Marañon General Hospital, Madrid

Department of Neurosurgery

Cesar La Cruz Pelea, Surgical Pathology, Gregorio Marañon General Hospital, Madrid

Department of Surgical Pathology. General Pathologist and expertise neuropathology and citology.

Published
2011-06-21
Section
Case Reports
Keywords:
melanoma, pineal gland, pineal melanoma, pineal tumours, primary tumours of pineal gland.
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How to Cite
Cedeño Díaz, O., Garcia Leal, R., & La Cruz Pelea, C. (2011). Primary pineal malignant melanoma. Clinics and Practice, 1(2), e31. https://doi.org/10.4081/cp.2011.e31