Fluctuations in C-reactive protein in a hepatoblastoma patient with thrombocytosis

  • Yuya Sato | syuya@dokkyomed.ac.jp
  • Ayaka Kokubu Department of Pediatrics, Dokkyo Medical University, Japan.
  • Keitaro Fukushima Department of Pediatrics, Dokkyo Medical University, Japan.
  • Mayuko Okuya Department of Pediatrics, Dokkyo Medical University, Japan.
  • Susumu Hagisawa Department of Pediatrics, Dokkyo Medical University, Japan.
  • Hidemitsu Kurosawa Department of Pediatrics, Dokkyo Medical University, Japan.
  • Kenichi Sugita Department of Pediatrics, Dokkyo Medical University, Japan.
  • Osamu Arisaka Department of Pediatrics, Dokkyo Medical University, Japan.
  • Kentaro Okamoto Department of Pediatric Surgery, Dokkyo Medical University, Japan.
  • Takashi Tsuchioka Department of Pediatric Surgery, Dokkyo Medical University, Japan.

Abstract

We observed the changes in serum levels of interleukin 6 (IL-6) and C-reactive protein (CRP) in a patient with hepatoblastoma exhibiting thrombocytosis. The concomitant changes of IL-6 and CRP concentrations after the initiation of chemotherapy, in the absence of infection, suggested that the IL-6, which is synthesized in hepatoblastoma cells and induces thrombocytosis, also stimulated CRP production in the present case. IL-6 is thought to play an important role in thrombocytosis in hepatoblastoma.

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Published
2011-08-09
Section
Case Reports
Keywords:
hepatoblastoma, thrombocytosis, C-reactive protein, interleukin-6.
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How to Cite
Sato, Y., Kokubu, A., Fukushima, K., Okuya, M., Hagisawa, S., Kurosawa, H., Sugita, K., Arisaka, O., Okamoto, K., & Tsuchioka, T. (2011). Fluctuations in C-reactive protein in a hepatoblastoma patient with thrombocytosis. Clinics and Practice, 1(3), e56. https://doi.org/10.4081/cp.2011.e56